Published this month (April, 2012), the new study entitled "Glyphosate induced cell death through apoptotic and authophagic mechanisms," investigated the potential brain-damaging effects of herbicides, which the authors stated "have been recognized as the main environmental factor associated with neuro-degenerative disorders, such as Parkinson’s disease."
- Endocrine Disruptor
- Aromatase Disruptor
- Glutathione Down-regulator
- Malondialdehyde Up-regulator
Once marketed as "safe as table salt" by Monsanto, the original patent holder and manufacturer of this glyphosate-based herbicide, evidence now indicates it is toxic to human DNA at concentrations diluted 450-fold lower than used in agricultural applications.
This study only adds to human case reports of glyphosate-poisoning and/or occupational exposure where neurological damage was a direct consequence. A 2011 case study published in the journal Parkinsonism Related Disorders, entitled "Parkinsonism after chronic occupational exposure to glyphosate," reported the following incident:
Another case study published in 2003 reported a case of parkinsonism subsequent to glyphosate exposure.
These case studies are also backed up by animal research. In the roundworm model of glyphosate exposure the chemical results in neurodegeneration directly associated with damage to the dopamine and GABA producing neurons. In the rat model, glyphosate exposure results in oxidative brain damage, particularly the substantia nigra, where the highest concentration of dopamine-producing cells reside, and which is the primary locus of neurological damage in Parkinson’s disease.