“This particular E.coli variation is a member of the O104 strain, and O104 strains are almost never (normally) resistant to antibiotics. In order for them to acquire this resistance, they must be repeatedly exposed to antibiotics in order to provide the "mutation pressure" that nudges them toward complete drug immunity.
So how, exactly, does a bacterial strain come into existence that's resistant to over a dozen antibiotics in eight different drug classes and features two deadly gene mutations plus ESBL enzyme capabilities?
There's really only one way this happens (and only one way) ~ you have to expose this strain of e.coli to all eight classes of antibiotics drugs. Usually this isn't done at the same time, of course: You first expose it to penicillin and find the surviving colonies which are resistant to penicillin. You then take those surviving colonies and expose them to tetracycline.
The surviving colonies are now resistant to both penicillin and tetracycline. You then expose them to a sulfa drug and collect the surviving colonies from that, and so on. It is a process of genetic selection done in a laboratory with a desired outcome. This is essentially how some bioweapons are engineered by the U.S. Army in its laboratory facility in Ft. Detrick, Maryland.”
“From an economic point of view World War II was, above all, a burst of deficit-financed government spending, on a scale that would never have been approved otherwise. Over the course of the war the federal government borrowed an amount equal to roughly twice the value of G.D.P. in 1940 as the equivalent of roughly $30 trillion today.…this slump can be cured. All it will take is a little bit of intellectual clarity, and a lot of political will.”